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EGID: an ensemble algorithm for improved genomic island detection in genomic sequences

机译:EGID:一种用于改进基因组序列中的基因组岛检测的集成算法

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摘要

Genomic islands (GIs) are genomic regions that are originally transferred from other organisms. The detection of genomic islands in genomes can lead to many applications in industrial, medical and environmental contexts. Existing computational tools for GIdetection suffer either low recall or low precision, thus leaving the room for improvement. In this paper, we report the development of our Ensemble algorithm for Genomic Island Detection (EGID). EGID utilizes the prediction results of existing computational tools, filters and generates consensus prediction results. Performance comparisons between our ensemble algorithmand existing programs have shown that our ensemble algorithm is better than any other program. EGID was implemented in Java, and was compiled and executed on Linux operating systems. EGID is freely available at http://www5.esu.edu/cpsc/bioinfo/software/EGID.
机译:基因岛(GIs)是最初从其他生物转移过来的基因组区域。基因组中基因组岛的检测可以导致在工业,医学和环境环境中的许多应用。现有的用于GI检测的计算工具的召回率或精度都较低,因此还有改进的余地。在本文中,我们报告了用于基因组岛检测(EGID)的Ensemble算法的发展。 EGID利用现有计算工具的预测结果,进行过滤并生成共识预测结果。我们的集成算法与现有程序之间的性能比较表明,我们的集成算法比其他任何程序都要好。 EGID用Java实现,并在Linux操作系统上编译和执行。 EGID可从http://www5.esu.edu/cpsc/bioinfo/software/EGID免费获得。

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